Hair Loss Treatments Target the Immune System

Hair Loss Treatments Target the Immune System

Volume 41 | September 2023 | Pages 1179–1185 By Charlotte Harrison Drugs commonly used in rheumatology, known as JAK inhibitors, are opening new treatment options for individuals with autoimmune-driven hair loss. Additionally, recent mechanistic insights are aiding scientists in addressing androgenic alopecia, the most prevalent cause of baldness. JAK Inhibitors and Alopecia Areata Two targeted…

Influence of climate factors on pediatric alopecia areata flares in Philadelphia, Pennsylvania

Influence of climate factors on pediatric alopecia areata flares in Philadelphia, Pennsylvania

Scientific Reports volume 11, Article number: 21034 (2021) Cite this article Abstract Patients with alopecia areata (AA) may experience episodic disease flares characterized by increasing hair loss that follow a seasonal pattern. However, no studies have examined whether specific climate factors contribute to the seasonal pattern of AA flares. Using Spearman rank correlation analyses, we assessed the association…

Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation

Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation

Scientific Reports volume 14, Article number: 4709 (2024) Cite this article Abstract Considerable global demand exists for the development of novel drugs for the treatment of alopecia. A recent report demonstrated that oxytocin promotes hair growth activity in human dermal papilla (DP) cells; however, its application in drugs or cosmetic products is challenging because rapid degradation and relatively…